After World War II “shocking” studies, daily doses of vitamin C need to be doubled



Recommended daily intake Vitamin C Scientists argued that the current level should be doubled, as it was informed by “shocking” World War II studies.

The World Health Organization recommends a daily intake of 45 mg, based on a 1944 study conducted by the Sorby Research Institute. The NHS advises a similar dose of 40 mg.

The now abolished research facility responsible for the guidelines was created to assess the nutritional levels of British citizens during times of food shortages.

Scientists at the University of Washington have informed the current guidelines and reviewed studies that described the method as “shocking.”

Current guidelines for vitamin C intake are not based on maximization General healthBut to stop scurvy, scientists say.

Modern scientists and medical professionals have failed to comprehensively review the 77-year-old study, according to the university, which has previously stated that recommended doses need to be upgraded.

In a study published in the American Journal of Clinical Nutrition, lead author Professor Philippe Fujoel said: “The Vitamin C experiment is a shocking study.

“I won’t fly now”

“They have long-term depleted people’s vitamin C levels, causing life-threatening emergencies. It now never flies.

“The results of a reanalysis of Sorby data suggest that WHO recommendations are too low to prevent scar weakness.”

He added: “A robust parametric analysis of test data revealed that an average daily intake of 95 mg of vitamin C was required to prevent weak scar strength in 97.5% of the population.

“Such vitamin C intake is more than double the WHO recommended daily intake of 45 mg of vitamin C, but is consistent with the National Academy of Medicine and (other) national writing panels.”

Vitamin C in citrus fruits and some vegetables helps protect cells and keep skin, bones, blood vessels, and cartilage healthy. It also helps to heal wounds.

Experiments based on only 20 volunteers

Professor Hujoel said: “When data from breakthrough trials became available, new statistical methods could not be reassessed, resulting in misleading explanations of vitamin C needed to prevent and treat collagen-related conditions. It may have been possible. “

The 1944 study was led by Sir Hans Adolf Krebs, a British-German biologist and Nobel Prize winner.

At that time, researchers conducted experiments to control and monitor vitamin C consumption in only 20 volunteers who refused to join the army.

Each conscientious objector was given different amounts of vitamin C to help the body produce collagen, and the wound was given to observe how quickly the scar healed.

This study found that the amount of vitamin C Navy members living on the diet needed to prevent the development of life-threatening scurvy, not the amount needed to improve overall health. The purpose was to confirm.

Scurvy was prevalent at the time, and some figures suggested that more members of the Navy were killed at sea by the disease than by the enemy.

Upon reviewing the study, University of Washington scholars used state-of-the-art statistical methods designed to handle small sample sizes that were not available at the time of the experiment.

This method, known as the “eyeball,” proved that the data evaluations used at the time were inadequate and misinterpreted.