Changes in menstruation after COVID-19 vaccination should be actively investigated: reproductive immunologists


A reproductive immunology instructor at Imperial College London said the question needs to be resolved by investigating the possible link between CCP virus vaccination and changes in menstruation.

In an editorial published on Thursday British Medical JournalDr. Victoria Mare may raise concerns that the vaccine could impair the opportunity for women to have children if they do not thoroughly investigate reports of menstrual changes after CCP (Chinese Communist Party) virus vaccination. He said he had sex.

By September 2, more than 30,000 menstrual disorders and unexpected vaginal bleeding after vaccination had been reported to the Medicines and Healthcare Products Regulatory Agency (MHRA) Yellow Card Monitoring Scheme for side effects, according to the editorial. rice field.

August 16th MHRA has released an update The “rigorous assessment completed so far” did not support the association of symptoms associated with changes in menstrual period with the CCP virus vaccine.

According to this document, there have been few reports of menstrual disorders and vaginal bleeding, both in relation to the number of people who have been vaccinated with the CCP virus and the general number of common menstrual disorders. That is.

He added that the reported disorders were transient in nature and there was no evidence to suggest that the vaccine would affect the ability to give birth and to give birth to children.

The man confirmed the MHRA statement, stating that most reported post-vaccination menstrual disorders occurred only one cycle before returning to normal.

She added that both unintended and unintended pregnancies in assisted reproductive technology are similar in patients vaccinated and unvaccinated in clinical trials.

However, men argue that further investigation is needed to eliminate uncertainty.

The Yellow Card Scheme relies on voluntary reporting of suspicious side effects or medical device accidents and is reported by medical professionals and the general public, including patients, caregivers, and parents.

The man said it was difficult to draw firm conclusions due to the nature of the system’s method of collecting information.

Italian vaccine
On May 15, 2021, a woman was vaccinated against COVID-19 at the Poliambulatorio Health Canter on the island of Lampedusa in the Pelagie Islands in southern Italy. (AlbertoPizzoli / AFP via Getty Images)

Reproductive immunology instructors suggested that, based on the available evidence, they do not believe the vaccine will affect women’s childbirth.

Currently, three CCP virus vaccines are available in the United Kingdom. Two of them (Pfizer-BioNTech and Spikevax (developed by Moderna)) are mRNA vaccines, and Oxford-AstraZenecajab is an adenoviral vector vaccine.

Menstrual change events occurred with all three vaccines. The man said that if there is an association between the vaccine and menstrual disorders, it suggests that it is likely the result of an immune response to vaccination rather than a particular vaccine component.

According to men, the menstrual cycle can be affected by immune activation in response to a variety of stimuli, including other vaccines and viral infections, including CCP virus infections.

In one study of women during menstruation, the editorial said that about a quarter of women infected with the CCP virus experienced menstrual turmoil.

Men believe that research can also help understand the mechanisms behind changes in menstruation after vaccination and help eliminate unnecessary fear and distrust of the vaccine.

“While the reported changes in the post-vaccination menstrual cycle are short-lived, solid research into this possible side effect remains important to the overall success of the vaccination program,” she writes.

The man called on UK health officials to follow the example of the National Institutes of Health, which made $ 1.67 million (£ 1.2 million) available to “encourage this important study” on August 30. ..

Dr. Jo Mountfield, vice president of the Royal College of Obstetricians and Gynaecologists, said the university “wants to guarantee women that changes usually return to normal after a cycle or two,” but needs further research into the possibilities. I also support sex. Association.

MHRA states that period problems can be caused by stressful life events, and changes in the menstrual cycle have been reported even after people are infected with the virus or suffer from so-called long COVIDs. I added.

Dr. Alison Cave, Chief Safety Officer at MHRA, said he “carefully monitors reports of suspected menstrual disorders” through a “robust” Yellow Card scheme.

“As outlined in Vaccine Safety Monitoring Strategies, the Yellow Card Scheme is one of several pieces of evidence to use when assessing vaccine safety,” she said.

“Based on current rigorous safety monitoring, women do not show that current evidence is associated with changes in women’s physiology or symptoms, suggesting that the COVID-19 vaccine affects childbirth. I can be confident that there is no such thing. This is also the conclusion of our expert Scientific Advisory Board, the Human Medicine Committee, “Cave said in a statement.

“While accompanied by discomfort or distress, menstrual problems are very common and stressful life events can disrupt a woman’s physiology. After being infected with COVID-19, and after being infected with a long COVID. Changes in the menstrual cycle have also been reported in women who have been infected, “she added.

“Our advice is that the benefits of vaccination outweigh the risks of most people.”

PA contributed to this report.

Lily Zhou