Clear link between AstraZeneca vaccine and rare blood clots in the brain, EMA formula tells paper



There is a link between the Rome-AstraZeneca COVID-19 vaccine and a very rare blood clot in the brain, but the possible causes are still unknown, a senior European Medicines Agency (EMA) official said Tuesday. Said in an interview.

“In my opinion, I can say that now. It’s clear that it has something to do with vaccines, but I still don’t know the cause of this reaction,” said EMA’s vaccine evaluation team chair. Marco Cavaleri told the Italian daily Il Messaggero when asked about the possible relationship between AstraZeneca injections and cases of stroke.

Cavaleri added that regulators wouldn’t be in a position to indicate the age of the individual to give AstraZeneca shots this week, but the EMA would say there is a link.

He did not provide evidence to support his comment.

AstraZeneca’s comments were not immediately available. Earlier, the study stated that vaccines do not increase the risk of blood clots.

Regulators are investigating 44 reports of a very rare cerebral coagulation disease known as cerebral sinus thrombosis (CVST) out of 9.2 million people in the European economic territory vaccinated with AstraZeneca. Consistently states that profits outweigh risks.

The World Health Organization also supports vaccines.

Last week, the review stated that it did not currently identify specific risk factors for these very rare events, such as age, gender, or a history of coagulopathy. A causal link to the vaccine has not been proven, but it is possible and further analysis is ongoing, officials said.

A high proportion of reported cases affected young and middle-aged women, but it did not conclude that the EMA was particularly at risk of firing AstraZeneca in this cohort. ..

The EMA will provide the latest information on the survey on Wednesday.

Several countries, including France, Germany and the Netherlands, have stopped using the vaccine for young people while the investigation continues.

Scientists are exploring several possibilities that could explain the very rare strokes that occur in individuals days or weeks after receiving the AstraZeneca vaccine.

European researchers have put forward one theory that vaccines rarely induce abnormal antibodies. Others are trying to understand if the case is associated with oral contraceptives.

However, many scientists have no clear evidence and it is not clear whether or why AstraZeneca’s vaccine causes problems that are not shared by other vaccines that target similar parts of the coronavirus. It states.

In another interview, Armando Genazzani, a member of the EMA’s Committee for Medicinal Products for Human Use (CHMP), told Rustampa daily that blood clots were “plausible” to correlate with the AstraZeneca vaccine.

Julia Segreti

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