How effective is the COVID-19 vaccine?Yahoo News explains


The Centers for Disease Control and Prevention said on Wednesday that more than 108 million Americans were vaccinated at least once with the coronavirus vaccine, and the country received an average of about 3 million vaccinations per day. Said. But how long is the vaccine valid? Dr. Kavita Patel, a contributor to Yahoo News Medical, explains.

Video transcript

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Kabita Patel: Innate immunity occurs after infection with SARS-COV-2, coronavirus, or COVID-19 infection. These are all the same. But it’s actually a way of your own body’s reaction and perception that antibodies will be developed if you are exposed to the virus again. Innate immunity really helps target what has infected you in the first place. This can be very different from the strains we see today, depending on what you are infected with.

And the immunity developed from the vaccine can actually react-we call it a polyclonal antibody reaction, which helped you induce very robust B and T cells. Even a response that means there are multiple exposures to your body through a vaccine that you are unaware of. These are various types of antibodies that occur even after a natural infection. But when it comes to vaccines, think this way. At higher levels, it gains more immunity to more diverse types of coronavirus peplomer. Therefore, we prepare for almost all possible types of coronavirus, including the current variants we are concerned about.

All current vaccines approved in the United States and vaccines worldwide are effective against currently known mutants. When I heard that the vaccine was said to be “not very effective,” it was when compared to the strain that existed a year ago. However, even with the most potent strains, the antibody response is sufficient to overcome the effects of that strain.

Fortunately, therefore, all licensed vaccines affect current variants, prevent mortality, and prevent severe hospitalization. But of course, this is something we have to watch carefully. That’s why we discuss what we call booster shots, test them, change vaccines, and see if we need to give everyone a booster at some point this year.

As such, there is one of the first real-world evidence data reports recently released by Pfizer, with more than 4,000 healthcare professionals surveyed and tracked, and immunity for at least 6 months, including some study participants. Showed to continue. Therefore, data showing not only thousands of participants in the United States alone, but also people from around the world show that antibodies remain at very high levels for at least 6 months after the second dose. I understand.

The only reason it is limited to 6 months is that it is the longest period we have had to see people since the vaccine was available or studied in people. There is no reason to believe that immunity lasts for at least 12 months and in some cases no longer. And that’s good news. Given that some Americans were vaccinated as early as December and hoped that their immunity would continue until next winter.

Therefore, different bodies have very different reactions. But what we know is that if you have a two-dose vaccine, the first vaccination actually introduces a kind of message to your body to make spike proteins. Your body is willing to make a spike protein, make an antibody against that spike protein, and recognize that it is a foreign body.

For the second dose, think of it as a unique type of booster. Here, the exact same message is reintroduced. This time, the body doesn’t have to wait. It recognizes that what is being introduced and produced by the cell is its peer-forming protein, informing the entire immune system that this is dangerous and triggering a reaction.

Therefore, it mimics influenza-type illnesses. Others have dramatic fever, tremors, and other symptoms. This usually lasts up to 36-48 hours and is expected to resolve. If that doesn’t work, talk to your doctor.

Just because you have no reaction does not mean that your body is not responding. Also, if you are really worried about no response, talk to your doctor. After all, immunity is broad, durable and long-lasting, at least for what we know today.

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