Pfizer COVID-19 vaccine can cause shingles in certain patients: study

New studies suggest that the mRNA Pfizer / BioNTech COVID-19 vaccine can cause shingles (or shingles) in certain patients with a single dose.

Israeli scientists say six women with autoimmune inflammatory rheumatic disease have received the first or second dose of COVID-19’s Pfizer vaccine, a disease caused by the CCP (Chinese Communist Party) virus. It was discovered that she had developed a herpes zoster infection within 3 to 14 days, according to Research It was published in the journal Rheumatoid Arthritis.

Researchers at the Tel Aviv Suraski Medical Center and Carmel Medical Center in Haifa have found that people with autoimmune-mediated rheumatoid arthritis are more likely to develop the disease.

Of the 491 patients, 6 or 1.2 percent experienced a viral infection, the researchers said. Five women developed the infection after the first Pfizer vaccine and one woman developed the infection after the second dose. Like the Moderna vaccine, the Pfizer vaccine requires two doses.

Researchers emphasized that one of the women had been vaccinated against herpes zoster two years before COVID-19 vaccination.

Shingles causes a painful rash that can affect any part of the body, but appears primarily as a single streak of blisters that wraps around both sides of the torso. Although this condition is not life-threatening, it can cause nerve damage and pain, skin infections, and loss of vision. Mayo Clinic..

It is different from the virus that causes cold and genital herpes, that is, sexually transmitted diseases.

However, it is unclear whether the Pfizer vaccine caused cases of shingles, the researchers said.

“At this point, we can’t say that the vaccine is the cause,” said Dr. Victoria Fuller, a senior researcher at the Tel Aviv Surahsky Medical Center, a rheumatologist. Jerusalem Post.. “It can be a trigger for some patients.”

“Cell-mediated immunity plays an important role in preventing varicella-zoster virus reactivation. Decreased cell-mediated immunity due to age and illness is associated with a decrease in varicella-zoster virus-specific T cells. , Interferes with immune surveillance and increases the risk of reactivation. Age is a major risk factor in 90% of cases of herpes zoster, “the researchers wrote in their study.

The average age of women in this study was 49, the youngest was 36 and the oldest was 61, with mild or stable rheumatic disease. Shingles is most common in people over the age of 50, and the risk of getting infected increases with age.

“That’s why we reported on it,” Furer said, saying that further research is needed on this issue to prove the cause and effect.

“We shouldn’t scare people,” the principal investigator told the press. “The overall message is to get vaccinated. It’s important to know.”