Rare hyperinflammatory syndrome has been reported in teens after COVID vaccination. Why experts don’t worry.


A new report by the US Centers for Disease Control and Prevention reports that it is potentially dangerous but highly dangerous in vaccinated adolescents as federal regulators continue to investigate the COVID-19 vaccine in children under the age of five. Cases of rare hyperinflammatory conditions have been identified.

Agency researchers have linked multiline inflammatory syndrome (COVID-19 infection) to vaccinated young people aged 12 to 20 years from December 14, 2020 to August 31, 2021. I studied cases of immune overreaction).

They found 21 reports of MIS-C in those who received at least one COVID-19 vaccine. According to a study published Tuesday at The Lancet Child & Adolescent Health. Six showed no evidence of previous coronavirus infection and all of the studies were vaccinated with the Pfizer-BioNTech vaccine.

The report may seem relevant at first, but experts dig deeper into the data and found that most cases were considered completely unvaccinated, so children and ten. He emphasizes the importance of vaccination for teenagers. The study also shows that unvaccinated adolescents are still more likely to develop MIS-C than vaccinated adolescents.

“At first glance, we take a step back and say,’Wait a minute, are these vaccines contributing to MIS-C?-Leader of the Texas Children’s Hospital.” It does the opposite to me. Prevention. We emphasize the points of inoculation. “

CDC researchers have determined that it is extremely rare to develop MIS-C after vaccination, suggesting that only 1 in 1 million vaccinated people in this age group will develop it. .. It is even more rare for vaccinated people to develop MIS-C without laboratory evidence of previous COVID-19 infection, about 0.3 per million.

Previous estimates suggest that MIS-C occurs in approximately 200 cases per million unvaccinated adolescents, according to the CDC.

“Even if there is a suspicious risk (with COVID vaccination), it is a much lower risk than getting sick without vaccination,” said Dr. Guliz Erdem, an infectious disease specialist and pediatric professor at a national children’s hospital. I am saying. Ohio State University.

Alejandro Garcia, 16, received the first dose of the Pfizer COVID-19 vaccine in West New York, NJ, on Monday, April 19, 2021.

Alejandro Garcia, 16, received the first dose of the Pfizer COVID-19 vaccine in West New York, NJ, on Monday, April 19, 2021.

The report found that 11 adolescents developed MIS-C after the first dose and 10 developed after the second dose. The median time from dosing to hospitalization was 8 days for those who received one vaccine and 5 days for those who received two doses.

The CDC guidelines consider that you have been fully vaccinated two weeks after your second vaccination.

“It tells me that these children were infected before they were vaccinated and did not have enough time to develop immunity with the vaccine before developing MIS-C.” Said Versalovic.

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Experts have made several hypotheses about the six cases of MIS-C found in adolescents without evidence of previous COVID-19 infection. For example, antibody tests may not have been sensitive enough to detect asymptomatic infections.

The authors of the study said that something else could have caused an overreactive immune response “accidentally after vaccination”, causing MIS-C symptoms such as fever, rash, red eye, and gastrointestinal symptoms. I am.

Regardless of possible explanations, experts state that this study supports COVID-19 vaccination and enhances the risk-benefit ratio. According to CDC data, only 57% of 12-17 year olds are fully vaccinated and parents are vaccinated against their children to protect them from the worst consequences of COVID-19, including MIS-C. I am urging you to receive it.

“It is clear that children who are only partially vaccinated are still susceptible to MIS-C,” Versalovic said. “Currently, we need to get qualified children vaccinated as soon as possible.”

Follow Adrianna Rodriguez on Twitter: @AdriannaUSAT.

Health and patient safety coverage at USA TODAY was partially made possible by grants from the Masimo Foundation for Ethics, Innovation and Competition in Healthcare. The Masimo Foundation does not provide editorial input.

This article was originally published in USA TODAY: Pfizer COVID Vaccine: CDC reports cases of MIS-C in vaccinated teens

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